Friday, February 17, 2017

Entry 5 – Bioinformatics and Cancer


Topic:


Cancer research is one of the areas of healthcare where bioinformatics is most widely used. BioMed Central addresses why bioinformatics is incredibly helpful in cancer research saying:
With increasing evidence that the interaction and network between genes and proteins play an important role in investigation of cancer molecular mechanisms, it is necessary and important to introduce a new concept of Systems Clinical Medicine into cancer research, to integrate systems biology, clinical science, omics-based technology, bioinformatics and computational science to improve diagnosis, therapies and prognosis of diseases.[i]
One of the ways in which medical professionals hope that bioinformatics will be able help advance cancer research is by using biomarkers in conjunction with patients symptoms and prognosis to find common links between certain genes and the severity and type of cancer the patient develops. Going forward, people hope to be able to use various algorithms to predict which individuals are more likely to develop cancer in their lifetime and attempt to resolve the issue before cancer is able to develop.

Important Terminology:


·      Bioinformatics - the collection, classification, storage, and analysis of biochemical and biological information using computers especially as applied in molecular genetics and genomics[ii]

·      Biomarker - a distinctive biological or biologically derived indicator (as a metabolite) of a process, event, or condition (as aging, disease, or oil formation)[iii]

Relation to Computer Science:


Computer science is one of the most important aspects in bioinformatics as the study of bioinformatics has become more popular. One particular reason that computer science is so important in bioinformatics is because establishing the infrastructure to handle and analyze all of the data and providing proper access and security to the data are critical.  Ensuring that a patient’s privacy is not compromised as the data is collected and analyzed has to be taken into consideration as well. One of the ways that this is being done is by assigning random numbers to patients and keeping the catalog of what numbers are associated with which patient on a separate, secured network. Computer scientists and data analysts are also a necessary part of the bioinformatics team because the majority of the healthcare providers involved are not educated on how to process and analyze large amounts of data.

Works Cited:


[i] "Cancer Bioinformatics: A New Approach to Systems Clinical Medicine." BMC Bioinformatics. BioMed Central, 01 May 2012. Web. 17 Feb. 2017.
[ii] "Bioinformatics." Merriam-Webster. Merriam-Webster, n.d. Web. 17 Feb. 2017.
[iii] "Biomarkers." Merriam-Webster. Merriam-Webster, n.d. Web. 17 Feb. 2017.

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